High-accuracy numerical models of Brownian thermal noise in thin mirror coatings

Brownian coating thermal noise in detector test masses is limiting the sensitivity of current gravitational-wave detectors on Earth. Therefore, accurate numerical models can inform the ongoing effort to minimize Brownian coating thermal noise in current and future gravitational-wave detectors. Such numerical models typically require significant computational resources and time, and often involve closed-source commercial codes. In contrast, open-source codes give complete visibility and control of the simulated physics and enable direct assessment of the numerical accuracy. In this article, we use the open-source SpECTRE numerical-relativity code and adopt a novel discontinuous Galerkin numerical method to model Brownian coating thermal noise. We demonstrate that SpECTRE achieves significantly higher accuracy than a previous approach at a fraction of the computational cost. Furthermore, we numerically model Brownian coating thermal noise in multiple sub-wavelength crystalline coating layers for the first time. Our new numerical method has the potential to enable fast exploration of realistic mirror configurations, and hence to guide the search for optimal mirror geometries, beam shapes and coating materials for gravitational-wave detectors.Comment: 9 pages, 5 figures. Results are reproducible with the ancillary input file

A scalable elliptic solver with task-based parallelism for the SpECTRE numerical relativity code

Elliptic partial differential equations must be solved numerically for many problems in numerical relativity, such as initial data for every simulation of merging black holes and neutron stars. Existing elliptic solvers can take multiple days to solve these problems at high resolution and when matter is involved, because they are either hard to parallelize or require a large amount of computational resources. Here we present a new solver for linear and non-linear elliptic problems that is designed to scale with resolution and to parallelize on computing clusters. To achieve this we employ a discontinuous Galerkin discretization, an iterative multigrid-Schwarz preconditioned Newton-Krylov algorithm, and a task-based parallelism paradigm. To accelerate convergence of the elliptic solver we have developed novel subdomain-preconditioning techniques. We find that our multigrid-Schwarz preconditioned elliptic solves achieve iteration counts that are independent of resolution, and our task-based parallel programs scale over 200 million degrees of freedom to at least a few thousand cores. Our new code solves a classic black-hole binary initial-data problem faster than the spectral code SpEC when distributed to only eight cores, and in a fraction of the time on more cores. It is publicly accessible in the next-generation SpECTRE numerical relativity code. Our results pave the way for highly-parallel elliptic solves in numerical relativity and beyond.Comment: 24 pages, 18 figures. Results are reproducible with the ancillary input file

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Simulating magnetized neutron stars with discontinuous Galerkin methods

Discontinuous Galerkin methods are popular because they can achieve high order where the solution is smooth, because they can capture shocks while needing only nearest-neighbor communication, and because they are relatively easy to formulate on complex meshes. We perform a detailed comparison of various limiting strategies presented in the literature applied to the equations of general relativistic magnetohydrodynamics. We compare the standard minmod/Lambda Pi(N) limiter, the hierarchical limiter of Krivodonova, the simple WENO limiter, the HWENO limiter, and a discontinuous Galerkin-finite-difference hybrid method. The ultimate goal is to understand what limiting strategies are able to robustly simulate magnetized Tolman-Oppenheimer-Volkoff stars without any fine-tuning of parameters. Among the limiters explored here, the only limiting strategy we can endorse is a discontinuous Galerkin-finitedifference hybrid method

SpECTRE

<p>SpECTRE is an open-source code for multi-scale, multi-physics problems in astrophysics and gravitational physics. In the future, we hope that it can be applied to problems across discipline boundaries in fluid dynamics, geoscience, plasma physics, nuclear physics, and engineering. It runs at petascale and is designed for future exascale computers.</p> <p>SpECTRE is being developed in support of our collaborative Simulating eXtreme Spacetimes (SXS) research program into the multi-messenger astrophysics of neutron star mergers, core-collapse supernovae, and gamma-ray bursts.</p&gt